What Are the Challenges in Analyzing Urinary Metabolites?
1. Complexity of Urine Matrix: Urine contains a wide variety of endogenous compounds that can interfere with the analysis. 2. Sensitivity and Specificity: Analytical methods need to be highly sensitive and specific to detect low levels of metabolites. 3. Inter-individual Variability: Differences in metabolism between individuals can complicate the interpretation of results.
