What are the Challenges in Diagnosing Prion Diseases?
Diagnosing prion diseases is challenging due to the lack of specific diagnostic tests that can detect prions early in the disease process. Current diagnostic techniques often rely on clinical symptoms, brain imaging, and detection of biomarkers in cerebrospinal fluid. However, definitive diagnosis typically requires a brain biopsy or autopsy. This poses significant hurdles for effective management and prevention of the spread of prion diseases.