What Are the Challenges in Establishing Toxic Thresholds?
One of the major challenges in establishing toxic thresholds is the complexity of biological systems. The same substance may have different thresholds in different species, making it difficult to extrapolate animal data to humans accurately. Additionally, chronic exposure to low doses might have cumulative effects that are not immediately apparent. Moreover, new chemicals and mixtures are constantly being introduced, requiring continuous research and updating of safety standards.
