What are the Challenges in Implementing Predictive Biomarkers?
Despite their potential, several challenges exist in implementing predictive biomarkers in toxicology. One major challenge is the complexity of biological systems, which makes it difficult to isolate specific biomarkers linked to particular outcomes. Additionally, there are technical and methodological challenges concerning the standardization and reproducibility of biomarker assays. Ethical and regulatory considerations also play a significant role, as there must be a consensus on how predictive biomarkers should be used in public health and clinical settings.