Despite its importance, metabolic toxicology faces several challenges, including:
Complexity of Metabolic Pathways: The human body has intricate metabolic networks, making it difficult to predict all possible outcomes of chemical metabolism. Inter-individual Variability: Variations among individuals can complicate the extrapolation of toxicological data. Limited Data on Metabolites: Often, the focus is on the parent compound, and less is known about the toxicity of metabolites.
