What are the Challenges in Preclinical Toxicity Testing?
One of the main challenges in preclinical toxicity testing is predicting human responses based on animal data. Differences in species physiology and metabolism can lead to discrepancies in drug effects. Moreover, developing reliable in vitro models that accurately mimic human systems remains a challenge. Regulatory requirements also add to the complexity, as different countries may have varied guidelines. Despite these challenges, advancements in biotechnology and computational modeling are paving the way for more predictive and ethical approaches.
