What Are the Challenges in Studying Immune-Mediated Damage?
Studying immune-mediated damage in toxicology presents several challenges. The complexity of the immune system, individual variability, and the myriad of potential toxins make it difficult to predict immune responses. Furthermore, the latency period between exposure and the onset of symptoms can complicate the identification of causal relationships. Animal models and in vitro studies can provide insights, but they may not fully replicate human immune responses. Advances in genomics and biomarkers are helping to improve our understanding of these mechanisms.