What are the Challenges in Studying MAPKs in Toxicology?
Studying MAPKs in toxicology poses several challenges. The complexity of MAPK signaling networks, with multiple isoforms and cross-talk between pathways, complicates the identification of specific components responsible for toxic effects. Additionally, the heterogeneity of cellular responses to toxicants and the influence of genetic and environmental factors further complicate the analysis. Advanced techniques in molecular biology and bioinformatics are crucial to unravel these complexities.
