What Are the Challenges in Studying the Ah Receptor?
Studying the Ah receptor presents several challenges. One major hurdle is the receptor's broad range of ligands, which include both naturally occurring and synthetic compounds. This diversity complicates the understanding of its biological functions and toxicological implications. Additionally, the Ah receptor's role in various physiological processes means that its complete inhibition could lead to unintended side effects. Researchers must also consider species-specific differences in Ah receptor biology, which can complicate the extrapolation of animal study results to humans.
