subacute and subchronic toxicity

What are the Challenges in Subacute and Subchronic Testing?

Despite their importance, these tests face certain challenges:
Ethical Concerns: The use of animals in testing raises ethical issues, prompting the development of alternative methods such as in vitro assays and computational models.
Extrapolation to Humans: Differences in metabolism and physiology between test animals and humans can complicate risk assessments.
Resource Intensive: These studies require significant time and financial resources, which can be a barrier for extensive testing.

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