What Are the Challenges in Toxicological Analysis of Illicit Drugs?
Toxicological analysis of illicit drugs presents several challenges. One major issue is the continuous emergence of new synthetic drugs, which may not be detected by standard tests. Another challenge is the potential for cross-reactivity in immunoassays, leading to false positives or negatives. Additionally, the complex matrices of biological samples can interfere with the detection and quantification of drugs, requiring sophisticated sample preparation techniques.