How Does Polydrug Use Affect Toxicological Findings?
Polydrug use, the concurrent use of multiple drugs, complicates toxicological analysis. The interactions between different drugs can alter their pharmacokinetics and pharmacodynamics, making it difficult to interpret results. For instance, the combination of opioids and benzodiazepines can enhance respiratory depression, increasing the risk of overdose. Toxicologists must consider these interactions when analyzing and reporting findings.