What Are the Clinical Manifestations of Aminoglycoside Toxicity?
Nephrotoxicity usually manifests as a gradual decline in renal function, often detected by an increase in serum creatinine levels. Patients may experience symptoms of acute kidney injury if not monitored carefully. Ototoxicity can present as tinnitus, hearing loss, or vertigo. These symptoms may occur during treatment or even after the therapy has been discontinued. Monitoring and early detection are crucial for minimizing these adverse effects.