Prevention of aminoglycoside toxicity involves several strategies. First, appropriate dosing and duration of therapy should be carefully determined based on the patient's renal function and the severity of the infection. Therapeutic drug monitoring is essential to ensure that serum concentrations remain within a safe range. Additionally, minimizing concurrent use of other nephrotoxic or ototoxic drugs can reduce the risk of toxicity. Patients should be closely monitored for any signs of adverse effects.
