What Are the Common Microstructural Changes Observed?
Common microstructural changes include alterations in cell morphology, damage to mitochondria, disruption of the cytoskeleton, nuclear changes, and modifications in the extracellular matrix. For instance, mitochondrial swelling, cristae disruption, and increased membrane permeability are typical responses to toxicant exposure. Additionally, changes in cell shape and size, loss of cellular adhesion, and apoptotic bodies are frequently observed.