The most commonly misused drugs include opioids, benzodiazepines, stimulants, and [alcohol](#). Opioids are frequently misused due to their potent analgesic properties, while benzodiazepines are often abused for their sedative effects. Stimulants, including prescription drugs like [Adderall](#) and illicit drugs like methamphetamine, are abused for their euphoric and performance-enhancing effects.