What Are the Consequences of Disrupted Neurotransmitter Release?
Disruptions in neurotransmitter release can lead to a wide range of neurological disorders and symptoms. For example, excessive release of excitatory neurotransmitters like glutamate can result in excitotoxicity, which is damaging to neurons and can lead to conditions such as seizures or neurodegenerative diseases. Conversely, inhibited release of neurotransmitters can cause deficits in signal transmission, potentially resulting in muscle weakness, paralysis, or cognitive impairments.