What are the Future Directions for iPSCs in Toxicology?
The field of iPSC-based toxicology is rapidly evolving, with several exciting future directions:
Personalized Medicine: iPSCs can be derived from individual patients, enabling personalized toxicity testing and precision medicine. Advanced 3D Models: Combining iPSCs with 3D culture techniques and organ-on-a-chip technology can create more complex and physiologically relevant models for toxicological studies. CRISPR and Gene Editing: Using CRISPR and other gene-editing technologies to modify iPSCs can help study the role of specific genes in toxicological responses. Integration with Omics Technologies: Integrating iPSC models with genomics, proteomics, and metabolomics can provide comprehensive insights into the molecular mechanisms of toxicity.