What are the Implications of Tubulin-Targeting Drugs?
Drugs that target tubulin, such as taxanes and vinca alkaloids, are widely used in chemotherapy because of their ability to halt cell division. However, their impact on normal cells can lead to side effects such as peripheral neuropathy, myelosuppression, and gastrointestinal issues. Understanding the balance between therapeutic efficacy and toxicity is crucial for optimizing treatment regimens and minimizing adverse effects.
