Vasopressin can interact with various drugs and substances, altering its pharmacodynamics. For instance, nonsteroidal anti-inflammatory drugs (NSAIDs) can potentiate its antidiuretic effect, increasing the risk of hyponatremia. Conversely, lithium can impair vasopressin's action, necessitating increased doses in patients with concurrent treatment. Understanding these interactions is vital for managing poisoned patients or those undergoing complex medical treatments.