What Are the Key Factors Influencing Toxicological Outcomes?
The outcome of toxicant exposure is influenced by several factors, including dose, duration, frequency of exposure, and the route of exposure. The metabolism of the organism also plays a critical role, as it can alter the chemical form of the toxicant, potentially increasing or decreasing its toxicity. Genetic factors, such as polymorphisms in metabolic enzymes, can also affect individual susceptibility to toxicants.
