The key processes in toxicology include absorption, distribution, metabolism, and excretion (ADME). These processes determine the fate of chemicals in the body:
Absorption: The entry of a chemical into the bloodstream, influenced by the route of exposure (e.g., oral, inhalation, dermal). Distribution: The dispersion of the chemical throughout the body's compartments, which depends on factors such as blood flow and tissue affinity. Metabolism: The body's biochemical transformation of the chemical, often via the liver enzymes, to facilitate excretion. Excretion: The removal of the substance from the body, primarily through urine, feces, or exhaled air.
