What Are the Limitations of Toxicological Testing?
Despite advances in toxicological research, there are inherent limitations to testing. In vivo studies often face ethical concerns and may not fully replicate human biological responses. In vitro tests, while useful for initial screenings, may not capture the complex interactions within a whole organism. Additionally, interspecies differences can affect the extrapolation of animal data to humans. These limitations emphasize the need for continued research and the development of alternative testing methods such as computational toxicology and high-throughput screening.
