What are the mechanisms behind toxin-induced depression?
The mechanisms behind toxin-induced depression are multifaceted. Neuroinflammation, oxidative stress, and disruption of neurotransmitter systems are common pathways. For example, neurotoxic substances can increase the production of pro-inflammatory cytokines, which can cross the blood-brain barrier and affect brain function. Additionally, oxidative stress can lead to neuronal damage, further exacerbating depressive symptoms.
