Why are Alcohol Dehydrogenases Important in Toxicology?
ADHs are crucial in the field of toxicology because they help in understanding how the body processes and detoxifies alcohol. The activity of these enzymes directly influences the toxicity of alcohols and their metabolites. For instance, ethanol is metabolized to acetaldehyde, a highly toxic substance, which is further broken down to less harmful acetic acid. The efficiency of this metabolic pathway can significantly affect an individual's susceptibility to alcohol-related toxicity and diseases.
