What are the mechanisms by which toxins affect bone remodeling?
Toxins can affect bone remodeling through various mechanisms. They can interfere with the activity of osteoblasts (cells responsible for bone formation) and osteoclasts (cells responsible for bone resorption). Toxins may induce oxidative stress, leading to damage of bone cells and the extracellular matrix. They can also disrupt the balance of calcium and other essential minerals, affecting normal bone metabolism and density.
