What are the Mechanisms of BNP Release in Toxic Exposure?
The release of BNP in response to toxic exposure primarily occurs due to increased ventricular wall stress. This stress can result from direct cardiotoxic effects, such as those caused by anthracyclines used in chemotherapy, or indirectly from systemic effects like hypertension caused by endocrine disruptors. Elevated BNP levels indicate the heart's compensatory response to maintain hemodynamic balance.
