What Are the Potential Toxicological Concerns with Tyrosine Kinase Inhibitors?
While TKIs have revolutionized cancer treatment, they can also present toxicological concerns. Common side effects include skin rashes, gastrointestinal issues, and cardiovascular complications. Long-term use can lead to more severe effects, such as liver damage and increased risk of developing secondary malignancies. Understanding these risks is essential for toxicologists to evaluate the overall safety and develop strategies to mitigate adverse effects.