Various mechanisms explain how endocrine disruptors achieve their effects. These include:
- Agonistic or Antagonistic Actions: Some disruptors bind to hormone receptors, either activating them (agonists) or blocking them (antagonists). - Altering Hormone Synthesis: Certain chemicals can increase or decrease the synthesis of hormones. - Modifying Hormone Degradation: Some disruptors affect the metabolic pathways that break down hormones, leading to altered levels in the body. - Transport and Binding Interference: Disruptors can impact the transport and binding proteins, influencing hormone bioavailability.
