What Are the Mechanisms of Toxicity Affecting the Heart?
The heart can be affected by toxins through several mechanisms. For example, toxins can disrupt the electrical conduction system, leading to arrhythmias. They can also impair mitochondrial function, reducing the energy supply to cardiac cells. Endothelial cells lining the blood vessels can be damaged by toxins, leading to impaired vasodilation and increased blood pressure. Understanding these mechanisms helps in the development of targeted therapies to counteract the toxic effects.