What Are the Mechanisms of Toxicity That Influence Differentiation?
Various mechanisms can lead to toxicity affecting cell differentiation, including:
Oxidative stress: Imbalance between free radicals and antioxidants can damage cellular components, impairing differentiation. DNA damage: Toxic agents can cause mutations or chromosomal aberrations that disrupt normal differentiation pathways. Epigenetic changes: Chemicals may alter DNA methylation or histone modification, affecting gene expression and cell fate decisions.
