What are the potential drug interactions with Topiramate?
Topiramate can interact with several medications, which may enhance its toxicity or reduce its efficacy. For instance, it can decrease the efficacy of oral contraceptives, necessitating alternative contraceptive measures. Concurrent use with other anticonvulsants like phenytoin or carbamazepine may alter serum levels of both drugs, requiring close monitoring. Co-administration with carbonic anhydrase inhibitors can increase the risk of metabolic acidosis.
