What Are the Potential Toxic Effects of Melatonin?
While rare, overdose or chronic use of melatonin can lead to several adverse effects. These may include headaches, dizziness, daytime drowsiness, and hormonal imbalances. In children, there is concern about potential impacts on puberty due to melatonin's influence on reproductive hormones. Animal studies have shown that extremely high doses can lead to toxicity, but these effects are not clearly established in humans.