What are the primary types of experimental models in toxicology?
Experimental models in toxicology are broadly categorized into in vitro, in vivo, and in silico approaches. In vitro models involve testing on cell cultures or tissues, offering a controlled environment for studying cellular responses to toxicants. In vivo models involve the use of whole organisms, such as rodents, to observe systemic effects and provide data on absorption, distribution, metabolism, and excretion (ADME). In silico models employ computational methods to predict toxicological endpoints based on chemical structure and biological data.
