Several risk factors are associated with the development of SCC. Prolonged exposure to UV radiation from the sun or tanning beds is a significant risk factor. Chemical carcinogens such as arsenic, polycyclic aromatic hydrocarbons (PAHs), and tobacco smoke are also implicated. Occupational hazards are important, particularly for individuals working with tar, soot, or certain industrial chemicals. Additionally, immunosuppression, whether due to medications or diseases like HIV, can increase susceptibility to SCC.
