Symptoms of kidney toxicity can vary based on the severity and duration of exposure. Common signs include decreased urine output, swelling in the extremities, fatigue, nausea, and changes in blood pressure. In severe cases, individuals may experience confusion, seizures, or even coma. It's essential to monitor kidney function through blood tests that measure creatinine and blood urea nitrogen (BUN) levels, especially when exposure to potential nephrotoxins is suspected.