While dimenhydrinate is generally safe when taken at recommended doses, it can cause toxic effects if misused or overdosed. Common symptoms of dimenhydrinate toxicity include drowsiness, confusion, blurred vision, dry mouth, and urinary retention. In severe cases, it can lead to hallucinations, seizures, respiratory depression, and even coma. The toxicity is primarily due to its diphenhydramine component, which can cross the blood-brain barrier and affect the central nervous system.