Dimenhydrinate is a widely used antihistamine and antiemetic medication, commonly known by the brand name Dramamine. It is primarily indicated for the prevention and treatment of nausea, vomiting, and dizziness caused by motion sickness. Dimenhydrinate is a combination of diphenhydramine and 8-chlorotheophylline. The latter is a mild stimulant that helps to counteract the sedative effects of diphenhydramine.