What are the Toxicological Concerns Associated with Metoclopramide?
While metoclopramide is generally safe when used as directed, adverse reactions can occur, particularly with prolonged use or overdose. One of the most significant toxicological concerns is the risk of tardive dyskinesia, a potentially irreversible condition characterized by involuntary, repetitive body movements. This risk increases with long-term use and higher doses, making it crucial to use the lowest effective dose for the shortest duration possible.