Toxicological studies have shown that linalool has a LD50 (lethal dose for 50% of the population) ranging from 2790 to 4600 mg/kg in rats, indicating relatively low acute toxicity. Chronic exposure studies are limited, but existing data suggest minimal risk under typical exposure scenarios. In vitro studies have examined its metabolites, finding that linalool is rapidly metabolized and excreted, reducing the risk of long-term bioaccumulation.
