There are several types of GSDs, each resulting from a specific enzyme deficiency. Some of the well-known types include:
Type I (Von Gierke's Disease): Caused by glucose-6-phosphatase deficiency, affecting the liver's ability to release glucose into the bloodstream. Type II (Pompe Disease): Due to acid alpha-glucosidase deficiency, leading to glycogen accumulation in lysosomes. Type III (Cori Disease): Results from a deficiency in the debranching enzyme, affecting both liver and muscle tissues. Type V (McArdle Disease): Affects muscle glycogen phosphorylase, impacting muscle energy availability.
