Tolerable Upper Intake Levels, commonly referred to as ULs, are the maximum daily intake amounts of a nutrient that are unlikely to cause adverse health effects for most individuals in the general population. These levels are established by health organizations such as the Institute of Medicine and are a key component of nutritional guidelines. ULs are particularly important in the context of Toxicology as they help mitigate the risk of toxicity due to excessive consumption of vitamins and minerals.