How Does Pathological Data Contribute to Risk Assessment?
Pathological data is a cornerstone of risk assessment in toxicology. It provides evidence of the adverse effects of a chemical, which is used to establish the No-Observed-Adverse-Effect Level (NOAEL) and the Lowest-Observed-Adverse-Effect Level (LOAEL). These values are critical for determining safe exposure limits and formulating regulatory guidelines. Pathological data also informs the identification of potential carcinogens, reproductive toxicants, and neurotoxic agents, contributing to a comprehensive evaluation of chemical risks.