Motion sickness arises from a conflict between the sensory inputs that the brain receives from the eyes, inner ear, and deeper body structures. The brain senses movement through these channels, and when they relay conflicting signals, it can lead to symptoms such as nausea, dizziness, and vomiting. This condition is often triggered when the inner ear senses movement that the eyes do not see, or vice versa, like when reading a book in a moving vehicle.