The use of medications to prevent or treat motion sickness is not without risks. Antihistamines and anticholinergics can cause side effects such as drowsiness, dry mouth, blurred vision, and impaired concentration. In some cases, these side effects can be significant enough to affect activities such as driving or operating machinery. Additionally, there is a risk of drug interactions when these medications are used with other drugs, necessitating careful management and consultation with healthcare professionals.