What Challenges are Associated with SAR in Toxicology?
Despite its benefits, SAR faces several challenges in toxicology. One major challenge is the complexity of biological systems, which can make it difficult to predict the behavior of chemicals accurately. Additionally, the quality and availability of data can limit the effectiveness of SAR models. There is also the challenge of interpreting SAR data, as small changes in chemical structure can lead to significant differences in biological activity. Furthermore, the extrapolation of SAR data from one species to another can be problematic due to differences in metabolism and toxicological responses.
