While substitution is a valuable strategy, it is not without challenges. Some of these include:
Availability of Alternatives: Suitable alternatives may not always be available or may require significant research and development. Performance Issues: Alternatives must meet the desired performance criteria, which can sometimes be difficult to achieve. Cost Implications: The cost of developing, testing, and implementing alternatives can be substantial. Regulatory Approval: New substances may require regulatory approval, which can be a time-consuming process.
