What Challenges are Faced in Biomarker Development?
Despite their potential, the development of biomarkers in toxicology faces significant challenges. One major challenge is the complexity of biological systems and the difficulty in distinguishing between normal variability and changes due to toxic exposure. Additionally, the validation process is resource-intensive and requires extensive research to confirm that a biomarker is specific and sensitive enough for its intended use. There is also a need for standardization in the methods used to measure and interpret biomarker data.
