Despite its importance, structural toxicology faces several challenges:
Complexity of Biological Systems: Biological systems are highly complex, and predicting how a chemical structure will interact with these systems is not always straightforward. Lack of Comprehensive Data: There is often limited data available for new chemicals, making it difficult to fully assess their toxic potential. Variability in Human Populations: Differences in genetics, age, and health status can affect how individuals respond to toxic substances.
