Several enzymes are responsible for catalyzing phase II reactions. Some of the key enzymes include: - UDP-glucuronosyltransferases (UGTs): Catalyze glucuronidation, attaching glucuronic acid to substrates. - Sulfotransferases (SULTs): Facilitate sulfation, adding sulfate groups. - N-acetyltransferases (NATs): Involved in acetylation, introducing acetyl groups. - Methyltransferases: Catalyze methylation, adding methyl groups. These enzymes are found predominantly in the liver but also in other tissues such as the intestines and kidneys.
